Combining PDE5 inhibitors can lead to better effects for men who may have not responded to a single medication or have not achieved the results they were looking for.
Research has demonstrated that combining Sildenafil and Tadalafil compared to taking only on-demand Sildenafil treatment led to significant improvements in erectile function (including erection quality, confidence, penetration, and sexual satisfaction). Plus, taking a combination of Sildenafil and Tadalafil also did not lead to an increase in side effects. It may minimize the risk of experiencing side effects from a single medication at a higher dosage.
This means with combination therapy, you can expect the maximum erection-enhancing effects with minimal side effects.